Google Mail (gmail) is the world's best email client.

Add distinct email addresses that all go to your mail email address

Google only supports plain-text signatures (hopefully they will add HTML support soon).

In the meantime, we need to use a browser extension to add HTML and graphics into an email signature.

To remove the WiseStamp advertisement beneath your signature, open the WiseStamp Settings tab and uncheck "Keep WiseStamp credit in the signatures".

For example, this is my signature

<div style="font-family: arial, helvetica, sans-serif;">--<br />George Vanous<br />CEO | <a href="http://www.thegamenet.com/">www.the<strong>game</strong>net.com</a>&nbsp;| skype: gvanous | GMT -8<br /><a href="http://www.thegamenet.com/"><img style="padding-top: 4px;" src="http://file.thegamenet.com/signatures/tgn-signature.jpg" alt="Join the new MMO gamer's network!" width="377" height="54" border="0" /></a></div>